Neutron radiation therapy for advanced thyroid cancers

Neutron radiation therapy for advanced thyroid cancers

Blog Article

Purpose: The aim of this study was to review institutional outcomes for advanced thyroid cancers treated with fast neutron radiation therapy (FNRT) and photon radiation therapy (RT).Methods and materials: In all, 62 consecutive patients were analyzed.Fifty-nine had stage IV disease.Twenty-three were treated with FNRT here and 39 with photon RT.

Median follow-up was 14 months.The primary endpoint was overall survival (OS).Results: There was no significant difference in median OS between FNRT and photon RT (26 vs 16 months; P =.49).

Patients with well-differentiated histologies had superior median OS with photon RT (17 vs 69 months; P =.04).There was a nonsignificant trend toward improved OS with FNRT for medullary and anaplastic histologies.Conclusions: Outcomes in grandpas best this study are in line with historical results.

There is an apparent detriment in OS with FNRT for well-differentiated histologies and a trend toward improved OS with medullary and anaplastic histologies that warrants further investigation.